DNA Microarrays In Herbal Drug Research | Pharmainfo.net
By Ravi Kumar
Natural products are gaining increased applications in drug discovery and development. Being chemically diverse they are able to modulate several targets simultaneously in a complex system. Analysis of gene expression becomes necessary for better understanding of molecular mechanisms. Conventional strategies for expression profiling are optimized for single gene analysis. DNA microarrays serve as suitable high throughput tool for simultaneous analysis of multiple genes. Major practical applicability of DNA microarrays remains in DNA mutation and polymorphism analysis.
CGH micro array is most widely used technique to detect chromosomal amplification and deletions in cancer.
This review highlights applications of DNA microarrays in pharmacodynamics, pharmacogenomics, toxicogenomics and quality control of herbal drugs and extracts.
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Hi, I'm Christine Hasinger, DOM. I’m an Oriental Medicine Practitioner of which a large part is utilizing natural herbal medicine. You see, we're Master Herbalists as well as Acupuncturists. A large part of our extensive training focuses on the preparation, making, use and prescribing of herbs and herbal formulas for a wide variety of health disorders and problems.